Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes

INTRODUCTION: Hypoxia is considered to be a positive influence on the healthy chondrocyte phenotype and cartilage matrix formation. However, hypoxia-inducible factors (HIFs) have been implicated in the pathogenesis of osteoarthritis (OA). Thus, we assessed whether healthy and OA chondrocytes have di...

Descripción completa

Detalles Bibliográficos
Autores principales: Markway, Brandon D, Cho, Holly, Johnstone, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979022/
https://www.ncbi.nlm.nih.gov/pubmed/23965235
http://dx.doi.org/10.1186/ar4272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979022/
https://www.ncbi.nlm.nih.gov/pubmed/23965235
http://dx.doi.org/10.1186/ar4272

Ejemplares similares