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A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis

INTRODUCTION: Aberrant turnover of the actin cytoskeleton is intimately associated with cancer cell migration and invasion. Frequently however, evidence is circumstantial, and a reliable assessment of the therapeutic significance of a gene product is offset by lack of inhibitors that target biologic...

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Detalles Bibliográficos
Autores principales: Van Impe, Katrien, Bethuyne, Jonas, Cool, Steven, Impens, Francis, Ruano-Gallego, David, De Wever, Olivier, Vanloo, Berlinda, Van Troys, Marleen, Lambein, Kathleen, Boucherie, Ciska, Martens, Evelien, Zwaenepoel, Olivier, Hassanzadeh-Ghassabeh, Gholamreza, Vandekerckhove, Joël, Gevaert, Kris, Fernández, Luis Ángel, Sanders, Niek N, Gettemans, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979033/
https://www.ncbi.nlm.nih.gov/pubmed/24330716
http://dx.doi.org/10.1186/bcr3585