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Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption

INTRODUCTION: The T allele of a single nucleotide polymorphism (SNP: rs2544390) in lipoprotein receptor-related protein 2 (LRP2) is associated with higher serum urate and risk of gout in Japanese individuals. SNP rs2544390 also interacts with alcohol consumption in determining hyperuricemia in this...

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Detalles Bibliográficos
Autores principales: Rasheed, Humaira, Phipps-Green, Amanda, Topless, Ruth, Hollis-Moffatt, Jade E, Hindmarsh, Jennie Harré, Franklin, Christopher, Dalbeth, Nicola, Jones, Peter B, White, Douglas HN, Stamp, Lisa K, Merriman, Tony R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979038/
https://www.ncbi.nlm.nih.gov/pubmed/24286387
http://dx.doi.org/10.1186/ar4366