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Adenosine-to-inosine RNA editing and human disease

A-to-I RNA editing is a post-transcriptional modification that converts adenosines to inosines in both coding and noncoding RNA transcripts. It is catalyzed by ADAR (adenosine deaminase acting on RNA) enzymes, which exist throughout the body but are most prevalent in the central nervous system. Inos...

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Detalles Bibliográficos
Autores principales: Slotkin, William, Nishikura, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979043/
https://www.ncbi.nlm.nih.gov/pubmed/24289319
http://dx.doi.org/10.1186/gm508