Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells

INTRODUCTION: The Runt-related transcription factor Runx2 is critical for skeletal development but is also aberrantly expressed in breast cancers, and promotes cell growth and invasion. A de-regulated serine/threonine kinase Akt signaling pathway is implicated in mammary carcinogenesis and cell surv...

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Detalles Bibliográficos
Autores principales: Tandon, Manish, Chen, Zujian, Pratap, Jitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979058/
https://www.ncbi.nlm.nih.gov/pubmed/24479521
http://dx.doi.org/10.1186/bcr3611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979058/
https://www.ncbi.nlm.nih.gov/pubmed/24479521
http://dx.doi.org/10.1186/bcr3611

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