Cargando…
Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells
INTRODUCTION: The Runt-related transcription factor Runx2 is critical for skeletal development but is also aberrantly expressed in breast cancers, and promotes cell growth and invasion. A de-regulated serine/threonine kinase Akt signaling pathway is implicated in mammary carcinogenesis and cell surv...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979058/ https://www.ncbi.nlm.nih.gov/pubmed/24479521 http://dx.doi.org/10.1186/bcr3611 |