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Collagenase-3 (MMP-13) deficiency protects C57BL/6 mice from antibody-induced arthritis

INTRODUCTION: Matrix metalloproteinases (MMPs) are important in tissue remodelling. Here we investigate the role of collagenase-3 (MMP-13) in antibody-induced arthritis. METHODS: For this study we employed the K/BxN serum-induced arthritis model. Arthritis was induced in C57BL/6 wild type (WT) and M...

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Detalles Bibliográficos
Autores principales: Singh, Anjana, Rajasekaran, Narendiran, Hartenstein, Bettina, Szabowski, Sibylle, Gajda, Mieczyslaw, Angel, Peter, Bräuer, Rolf, Illges, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979078/
https://www.ncbi.nlm.nih.gov/pubmed/24369907
http://dx.doi.org/10.1186/ar4423