Cargando…

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease

APOE, which encodes apolipoprotein E, is the most prevalent and best established genetic risk factor for late-onset Alzheimer’s disease. Current understanding of Alzheimer’s disease pathophysiology posits an important role for apolipoprotein E in the disease cascade via its interplay with β-amyloid....

Descripción completa

Detalles Bibliográficos
Autores principales: Wolf, Andrew B, Valla, Jon, Bu, Guojun, Kim, Jungsu, LaDu, Mary Jo, Reiman, Eric M, Caselli, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979087/
https://www.ncbi.nlm.nih.gov/pubmed/23998393
http://dx.doi.org/10.1186/alzrt204