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Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease

APOE, which encodes apolipoprotein E, is the most prevalent and best established genetic risk factor for late-onset Alzheimer’s disease. Current understanding of Alzheimer’s disease pathophysiology posits an important role for apolipoprotein E in the disease cascade via its interplay with β-amyloid....

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Detalles Bibliográficos
Autores principales:	Wolf, Andrew B, Valla, Jon, Bu, Guojun, Kim, Jungsu, LaDu, Mary Jo, Reiman, Eric M, Caselli, Richard J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979087/ https://www.ncbi.nlm.nih.gov/pubmed/23998393 http://dx.doi.org/10.1186/alzrt204

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