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De Novo Synthesis of Multisubstituted Aryl Amines Using Alkene Cross Metathesis

[Image: see text] The olefin cross-metathesis reaction allows rapid access to 1,5-dicarbonyl intermediates which, upon treatment with a primary or secondary amine, allow the synthesis of a range of multisubstituted carbocyclic aryl amines. This de novo arene synthesis yields nonclassical substitutio...

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Detalles Bibliográficos
Autores principales: Tatton, Matthew R., Simpson, Iain, Donohoe, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979090/
https://www.ncbi.nlm.nih.gov/pubmed/24646289
http://dx.doi.org/10.1021/ol500441q