Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection

The combination of an E2 ubiquitin-conjugating enzyme with an E3 ubiquitin-ligase is essential for ubiquitin modification of a substrate. Moreover, the pairing dictates both the substrate choice and the modification type. The molecular details of generic E3-E2 interactions are well established. Neve...

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Detalles Bibliográficos
Autores principales: Hodson, Charlotte, Purkiss, Andrew, Miles, Jennifer Anne, Walden, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979106/
https://www.ncbi.nlm.nih.gov/pubmed/24389026
http://dx.doi.org/10.1016/j.str.2013.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979106/
https://www.ncbi.nlm.nih.gov/pubmed/24389026
http://dx.doi.org/10.1016/j.str.2013.12.004

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