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Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection

The combination of an E2 ubiquitin-conjugating enzyme with an E3 ubiquitin-ligase is essential for ubiquitin modification of a substrate. Moreover, the pairing dictates both the substrate choice and the modification type. The molecular details of generic E3-E2 interactions are well established. Neve...

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Detalles Bibliográficos
Autores principales:	Hodson, Charlotte, Purkiss, Andrew, Miles, Jennifer Anne, Walden, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Short Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979106/ https://www.ncbi.nlm.nih.gov/pubmed/24389026 http://dx.doi.org/10.1016/j.str.2013.12.004

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