Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures

Advances in sequencing have enabled the identification of mutations acquired by bacterial pathogens during infection(1-10). However, it remains unclear whether adaptive mutations fix in the population or lead to pathogen diversification within the patient(11,12). Here, we study the genotypic diversi...

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Detalles Bibliográficos
Autores principales: Lieberman, Tami D., Flett, Kelly B., Yelin, Idan, Martin, Thomas R., McAdam, Alexander J., Priebe, Gregory P., Kishony, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979468/
https://www.ncbi.nlm.nih.gov/pubmed/24316980
http://dx.doi.org/10.1038/ng.2848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979468/
https://www.ncbi.nlm.nih.gov/pubmed/24316980
http://dx.doi.org/10.1038/ng.2848

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