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Involvement of the Akt/NF-κB Pathways in the HTNV-Mediated Increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs

BACKGROUND: Hantaan virus (HTNV) infection causes a severe form of HFRS(hemorrhagic fever with renal syndrome)in Asia. Although HTNV has been isolated for nearly forty years, the pathogenesis of HFRS is still unknown, and little is known regarding the signaling pathway that is activated by the virus...

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Detalles Bibliográficos
Autores principales: Yu, Haitao, Jiang, Wei, Du, Hong, Xing, Yuan, Bai, Guangzhen, Zhang, Ye, Li, Yu, Jiang, Hong, Zhang, Ying, Wang, Jiuping, Wang, Pingzhong, Bai, Xuefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979720/
https://www.ncbi.nlm.nih.gov/pubmed/24714064
http://dx.doi.org/10.1371/journal.pone.0093810