Synergistic and Antagonistic Drug Combinations Depend on Network Topology

Drug combinations may exhibit synergistic or antagonistic effects. Rational design of synergistic drug combinations remains a challenge despite active experimental and computational efforts. Because drugs manifest their action via their targets, the effects of drug combinations should depend on the...

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Detalles Bibliográficos
Autores principales: Yin, Ning, Ma, Wenzhe, Pei, Jianfeng, Ouyang, Qi, Tang, Chao, Lai, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979733/
https://www.ncbi.nlm.nih.gov/pubmed/24713621
http://dx.doi.org/10.1371/journal.pone.0093960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979733/
https://www.ncbi.nlm.nih.gov/pubmed/24713621
http://dx.doi.org/10.1371/journal.pone.0093960

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