Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury

The transcription factor p53 mediates the apoptosis of post-mitotic neurons exposed to a wide range of stress stimuli. The apoptotic activity of p53 is tightly regulated by the apoptosis-stimulating proteins of p53 (ASPP) family members: ASPP1, ASPP2 and iASPP. We previously showed that the pro-apop...

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Detalles Bibliográficos
Autores principales: Wilson, Ariel M., Chiodo, Vince A., Boye, Sanford L., Brecha, Nicholas C., Hauswirth, William W., Di Polo, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979759/
https://www.ncbi.nlm.nih.gov/pubmed/24714389
http://dx.doi.org/10.1371/journal.pone.0094175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979759/
https://www.ncbi.nlm.nih.gov/pubmed/24714389
http://dx.doi.org/10.1371/journal.pone.0094175

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