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Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury
The transcription factor p53 mediates the apoptosis of post-mitotic neurons exposed to a wide range of stress stimuli. The apoptotic activity of p53 is tightly regulated by the apoptosis-stimulating proteins of p53 (ASPP) family members: ASPP1, ASPP2 and iASPP. We previously showed that the pro-apop...
Autores principales: | Wilson, Ariel M., Chiodo, Vince A., Boye, Sanford L., Brecha, Nicholas C., Hauswirth, William W., Di Polo, Adriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979759/ https://www.ncbi.nlm.nih.gov/pubmed/24714389 http://dx.doi.org/10.1371/journal.pone.0094175 |
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