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Memo Has a Novel Role in S1P Signaling and Crucial for Vascular Development

Memo is a conserved protein that was identified as an essential mediator of tumor cell motility induced by receptor tyrosine kinase activation. Here we show that Memo null mouse embryonic fibroblasts (MEFs) are impaired in PDGF-induced migration and this is due to a defect in sphingosine-1-phosphate...

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Detalles Bibliográficos
Autores principales: Kondo, Shunya, Bottos, Alessia, Allegood, Jeremy C., Masson, Regis, Maurer, Francisca G., Genoud, Christel, Kaeser, Patrick, Huwiler, Andrea, Murakami, Masato, Spiegel, Sarah, Hynes, Nancy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979765/
https://www.ncbi.nlm.nih.gov/pubmed/24714781
http://dx.doi.org/10.1371/journal.pone.0094114