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Preparation and in vitro/in vivo characterization of enteric-coated nanoparticles loaded with the antihypertensive peptide VLPVPR

Our previous study revealed that the peptide Val-Leu-Pro-Val-Pro-Arg (VLPVPR), which was prepared using deoxyribonucleic acid recombinant technology, effectively decreased the blood pressure of spontaneous hypertensive rats; however, the effect only lasts 6 hours, likely due to its low absorption in...

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Detalles Bibliográficos
Autores principales: Sun, Haiyan, Liu, Dong, Li, Yan, Tang, Xuwei, Cong, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979782/
https://www.ncbi.nlm.nih.gov/pubmed/24729706
http://dx.doi.org/10.2147/IJN.S56092