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VEGF-Production by CCR2-Dependent Macrophages Contributes to Laser-Induced Choroidal Neovascularization

Age-related macular degeneration (AMD) is the most prevalent cause of blindness in the elderly, and its exsudative subtype critically depends on local production of vascular endothelial growth factor A (VEGF). Mononuclear phagocytes, such as macrophages and microglia cells, can produce VEGF. Their p...

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Detalles Bibliográficos
Autores principales: Krause, Torsten A., Alex, Anne F., Engel, Daniel R., Kurts, Christian, Eter, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979804/
https://www.ncbi.nlm.nih.gov/pubmed/24714223
http://dx.doi.org/10.1371/journal.pone.0094313