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Identification of Resveratrol Oligomers as Inhibitors of Cystic Fibrosis Transmembrane Conductance Regulator by High-Throughput Screening of Natural Products from Chinese Medicinal Plants

Inhibitors of cystic fibrosis transmembrane conductance regulator (CFTR) have been widely used for characterizing CFTR function in epithelial fluid transport and in diseases such as secretory diarrhea, polycystic kidney disease and cystic fibrosis. Few small molecule CFTR inhibitors have been discov...

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Detalles Bibliográficos
Autores principales: Zhang, Yaofang, Yu, Bo, Sui, Yujie, Gao, Xin, Yang, Hong, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979805/
https://www.ncbi.nlm.nih.gov/pubmed/24714160
http://dx.doi.org/10.1371/journal.pone.0094302