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Identification of Resveratrol Oligomers as Inhibitors of Cystic Fibrosis Transmembrane Conductance Regulator by High-Throughput Screening of Natural Products from Chinese Medicinal Plants
Inhibitors of cystic fibrosis transmembrane conductance regulator (CFTR) have been widely used for characterizing CFTR function in epithelial fluid transport and in diseases such as secretory diarrhea, polycystic kidney disease and cystic fibrosis. Few small molecule CFTR inhibitors have been discov...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979805/ https://www.ncbi.nlm.nih.gov/pubmed/24714160 http://dx.doi.org/10.1371/journal.pone.0094302 |