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Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer

Increasing health care costs in the US are due in a large part to the increasing prevalence of chronic diseases in an aging population. Current therapeutic strategies for treating chronic diseases alleviate symptoms allowing patients to live longer with these diseases, but they do little, however, t...

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Detalles Bibliográficos
Autores principales: Overley-Adamson, Beth, Artlett, Carol M, Stephens, Connie, Sassi-Gaha, Sihem, Weis, Ransome D, Thacker, James D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979823/
https://www.ncbi.nlm.nih.gov/pubmed/24496016
http://dx.doi.org/10.4161/cbt.27820