Enhanced Production of Chikungunya Virus-Like Particles Using a High-pH Adapted Spodoptera frugiperda Insect Cell Line

Chikungunya virus-like particles (VLPs) have potential to be used as a prophylactic vaccine based on testing in multiple animal models and are currently being evaluated for human use in a Phase I clinical trial. The current method for producing these enveloped alphavirus VLPs by transient gene expre...

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Detalles Bibliográficos
Autores principales: Wagner, James M., Pajerowski, J. David, Daniels, Christopher L., McHugh, Patrick M., Flynn, Jessica A., Balliet, John W., Casimiro, Danilo R., Subramanian, Shyamsundar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979839/
https://www.ncbi.nlm.nih.gov/pubmed/24713807
http://dx.doi.org/10.1371/journal.pone.0094401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979839/
https://www.ncbi.nlm.nih.gov/pubmed/24713807
http://dx.doi.org/10.1371/journal.pone.0094401

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