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Enhanced Production of Chikungunya Virus-Like Particles Using a High-pH Adapted Spodoptera frugiperda Insect Cell Line
Chikungunya virus-like particles (VLPs) have potential to be used as a prophylactic vaccine based on testing in multiple animal models and are currently being evaluated for human use in a Phase I clinical trial. The current method for producing these enveloped alphavirus VLPs by transient gene expre...
Autores principales: | Wagner, James M., Pajerowski, J. David, Daniels, Christopher L., McHugh, Patrick M., Flynn, Jessica A., Balliet, John W., Casimiro, Danilo R., Subramanian, Shyamsundar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979839/ https://www.ncbi.nlm.nih.gov/pubmed/24713807 http://dx.doi.org/10.1371/journal.pone.0094401 |
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