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Prevention of CpG-Induced Pregnancy Disruption by Adoptive Transfer of In Vitro-Induced Regulatory T Cells

OBJECTIVE: To elucidate the mechanism by which embryo-resorption and preterm birth were enhanced by pathogenic CpG motif and to develop a counter strategy for normal pregnancy outcome. METHODS: This is an animal model-based study. In pregnant nonobese diabetic (NOD) mice and wild-type (WT) mice in t...

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Detalles Bibliográficos
Autores principales: Lin, Yi, Liu, Xiaorui, Shan, Bin, Wu, Ji, Sharma, Surendra, Sun, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979847/
https://www.ncbi.nlm.nih.gov/pubmed/24714634
http://dx.doi.org/10.1371/journal.pone.0094702