Cockayne Syndrome: Varied Requirement of Transcription-Coupled Nucleotide Excision Repair for the Removal of Three Structurally Different Adducts from Transcribed DNA

Hereditary defects in the transcription-coupled nucleotide excision repair (TC-NER) pathway of damaged DNA cause severe neurodegenerative disease Cockayne syndrome (CS), however the origin and chemical nature of the underlying DNA damage had remained unknown. To find out, to which degree the structu...

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Detalles Bibliográficos
Autores principales: Kitsera, Nataliya, Gasteiger, Karola, Lühnsdorf, Bork, Allgayer, Julia, Epe, Bernd, Carell, Thomas, Khobta, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979923/
https://www.ncbi.nlm.nih.gov/pubmed/24713864
http://dx.doi.org/10.1371/journal.pone.0094405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979923/
https://www.ncbi.nlm.nih.gov/pubmed/24713864
http://dx.doi.org/10.1371/journal.pone.0094405

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