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Stimulation of I(Ca) by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes()

L-type Ca channels (LTCC), which play a key role in cardiac excitation–contraction coupling, are located predominantly at the transverse (t-) tubules in ventricular myocytes. Caveolae and the protein caveolin-3 (Cav-3) are also present at the t-tubules and have been implicated in localizing a number...

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Detalles Bibliográficos
Autores principales: Bryant, Simon, Kimura, Tomomi E., Kong, Cherrie H.T., Watson, Judy J., Chase, Anabelle, Suleiman, M. Saadeh, James, Andrew F., Orchard, Clive H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980375/
https://www.ncbi.nlm.nih.gov/pubmed/24412535
http://dx.doi.org/10.1016/j.yjmcc.2013.12.026