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‘Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption’

Disruption of adenylyl cyclase type 5 (AC5) knockout (KO) is a novel model for longevity. Because malignancy is a major cause of death and reduced lifespan in mice, the goal of this investigation was to examine the role of AC5KO in protecting against cancer. There have been numerous discoveries in g...

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Detalles Bibliográficos
Autores principales: De Lorenzo, Mariana S, Chen, Wen, Baljinnyam, Erdene, Carlini, María J, La Perle, Krista, Bishop, Sanford P, Wagner, Thomas E, Rabson, Arnold B, Vatner, Dorothy E, Puricelli, Lydia I, Vatner, Stephen F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980454/
https://www.ncbi.nlm.nih.gov/pubmed/23957304
http://dx.doi.org/10.1111/acel.12152