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‘Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption’
Disruption of adenylyl cyclase type 5 (AC5) knockout (KO) is a novel model for longevity. Because malignancy is a major cause of death and reduced lifespan in mice, the goal of this investigation was to examine the role of AC5KO in protecting against cancer. There have been numerous discoveries in g...
Autores principales: | De Lorenzo, Mariana S, Chen, Wen, Baljinnyam, Erdene, Carlini, María J, La Perle, Krista, Bishop, Sanford P, Wagner, Thomas E, Rabson, Arnold B, Vatner, Dorothy E, Puricelli, Lydia I, Vatner, Stephen F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980454/ https://www.ncbi.nlm.nih.gov/pubmed/23957304 http://dx.doi.org/10.1111/acel.12152 |
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