Specific Inhibition of the VEGFR-3 Tyrosine Kinase by SAR131675 Reduces Peripheral and Tumor Associated Immunosuppressive Myeloid Cells

Myeloid derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) represent prominent components in cancer progression. We previously showed that inhibition of the VEGFR-3 pathway by SAR131675 leads to reduction of TAM infiltration and tumor growth. Here, we found that treatment with...

Descripción completa

Detalles Bibliográficos
Autores principales: Espagnolle, Nicolas, Barron, Pauline, Mandron, Marie, Blanc, Isabelle, Bonnin, Jacques, Agnel, Magali, Kerbelec, Erwan, Herault, Jean Pascal, Savi, Pierre, Bono, Françoise, Alam, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980599/
https://www.ncbi.nlm.nih.gov/pubmed/24589997
http://dx.doi.org/10.3390/cancers6010472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980599/
https://www.ncbi.nlm.nih.gov/pubmed/24589997
http://dx.doi.org/10.3390/cancers6010472

Ejemplares similares