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Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex

Focal Adhesion Kinase (FAK) is a non-receptor kinase that plays an important role in many cellular processes: adhesion, proliferation, invasion, angiogenesis, metastasis and survival. Recently, we have shown that Roslin 2 or R2 (1-benzyl-15,3,5,7-tetraazatricyclo[3.3.1.1~3,7~]decane) compound disrup...

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Detalles Bibliográficos
Autores principales: Golubovskaya, Vita M., Ho, Baotran, Conroy, Jeffrey, Liu, Song, Wang, Dan, Cance, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980603/
https://www.ncbi.nlm.nih.gov/pubmed/24452144
http://dx.doi.org/10.3390/cancers6010166