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Loss of STAT3 in Lymphoma Relaxes NK Cell-Mediated Tumor Surveillance

The transcription factors and proto-oncogenes STAT3 and STAT5 are highly activated in hematological malignancies and represent promising therapeutic targets. Whereas the importance of STAT5 as tumor promoter is beyond doubt, the role of STAT3 in hematological cancers is less well understood. Both, e...

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Detalles Bibliográficos
Autores principales: Putz, Eva Maria, Hoelzl, Maria Agnes, Baeck, Julia, Bago-Horvath, Zsuzsanna, Schuster, Christian, Reichholf, Brian, Kern, Daniela, Aberger, Fritz, Sexl, Veronika, Hoelbl-Kovacic, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980609/
https://www.ncbi.nlm.nih.gov/pubmed/24473086
http://dx.doi.org/10.3390/cancers6010193