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Monitoring and Inhibiting MT1-MMP during Cancer Initiation and Progression

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a zinc-dependent type-I transmembrane metalloproteinase involved in pericellular proteolysis, migration and invasion. Numerous substrates and binding partners have been identified for MT1-MMP, and its role in collagenolysis appears crucial for tu...

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Detalles Bibliográficos
Autores principales: Pahwa, Sonia, Stawikowski, Maciej J., Fields, Gregg B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980612/
https://www.ncbi.nlm.nih.gov/pubmed/24549119
http://dx.doi.org/10.3390/cancers6010416