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Structural Perspective on Enzymatic Halogenation
[Image: see text] Simple halogen substituents frequently afford key structural features that account for the potency and selectivity of natural products, including antibiotics and hormones. For example, when a single chlorine atom on the antibiotic vancomycin is replaced by hydrogen, the resulting a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980734/ https://www.ncbi.nlm.nih.gov/pubmed/18774824 http://dx.doi.org/10.1021/ar800088r |