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BMP-2 Overexpression Augments Vascular Smooth Muscle Cell Motility by Upregulating Myosin Va via Erk Signaling

Background. The disruption of physiologic vascular smooth muscle cell (VSMC) migration initiates atherosclerosis development. The biochemical mechanisms leading to dysfunctional VSMC motility remain unknown. Recently, cytokine BMP-2 has been implicated in various vascular physiologic and pathologic...

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Detalles Bibliográficos
Autores principales: Zhang, Ming, Yang, Min, Liu, Li-ping, Lau, Wayne Bond, Gao, Hai, Xin, Man-kun, Su, Li-Xiao, Wang, Jian, Cheng, Shu-Juan, Fan, Qian, Liu, Jing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980867/
https://www.ncbi.nlm.nih.gov/pubmed/24790701
http://dx.doi.org/10.1155/2014/294150