TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression

Breast cancer progression and metastasis have been linked to abnormal signaling by transforming growth factor-β (TGF-β) cytokines. In early-stage breast cancers, TGF-β exhibits tumor suppressor activity by repressing cell proliferation and inducing cell death, whereas in advanced-stage tumors, TGF-β...

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Detalles Bibliográficos
Autores principales: DAROQUI, MARÍA CECILIA, VAZQUEZ, PAULA, DE KIER JOFFÉ, ELISA BAL, BAKIN, ANDREI V., PURICELLI, LYDIA I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981025/
https://www.ncbi.nlm.nih.gov/pubmed/22614218
http://dx.doi.org/10.3892/or.2012.1813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981025/
https://www.ncbi.nlm.nih.gov/pubmed/22614218
http://dx.doi.org/10.3892/or.2012.1813

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