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Tpo1-mediated spermine and spermidine export controls cell cycle delay and times antioxidant protein expression during the oxidative stress response

Cells counteract oxidative stress by altering metabolism, cell cycle and gene expression. However, the mechanisms that coordinate these adaptations are only marginally understood. Here we provide evidence that timing of these responses in yeast requires export of the polyamines spermidine and spermi...

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Detalles Bibliográficos
Autores principales: Krüger, Antje, Vowinckel, Jakob, Mülleder, Michael, Grote, Phillip, Capuano, Floriana, Bluemlein, Katharina, Ralser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981086/
https://www.ncbi.nlm.nih.gov/pubmed/24136413
http://dx.doi.org/10.1038/embor.2013.165