Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome

Patient-specific induced pluripotent stem cells (iPSCs) will assist research on genetic cardiac maladies if the disease phenotype is recapitulated in vitro. However, genetic background variations may confound disease traits, especially for disorders with incomplete penetrance, such as long-QT syndro...

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Detalles Bibliográficos
Autores principales: Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981141/
https://www.ncbi.nlm.nih.gov/pubmed/24213244
http://dx.doi.org/10.1038/emboj.2013.240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981141/
https://www.ncbi.nlm.nih.gov/pubmed/24213244
http://dx.doi.org/10.1038/emboj.2013.240

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