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Temporal- and Location-Specific Alterations of the GABA Recycling System in Mecp2 KO Mouse Brains

Rett syndrome (RTT), associated with mutations in methyl-CpG-binding protein 2 (Mecp2), is linked to diverse neurological symptoms such as seizures, motor disabilities, and cognitive impairments. An altered GABAergic system has been proposed as one of many underlying pathologies of progressive neuro...

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Detalles Bibliográficos
Autores principales: Kang, Seok K, Kim, Shin Tae, Johnston, Michael V, Kadam, Shilpa D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981570/
https://www.ncbi.nlm.nih.gov/pubmed/24737935
http://dx.doi.org/10.4137/JCNSD.S14012