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The structural basis of transferrin sequestration by transferrin-binding protein B

Neisseria meningitidis, the causative agent of bacterial meningitis, acquires the essential element iron from the host glycoprotein transferrin (Tf) during infection via a surface Tf receptor system composed of proteins TbpA and TbpB. Here in we present the crystal structures of TbpB from N. meningi...

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Detalles Bibliográficos
Autores principales: Calmettes, Charles, Alcantara, Joenel, Yu, Rong-Hua, Schryvers, Anthony B., Moraes, Trevor F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981719/
https://www.ncbi.nlm.nih.gov/pubmed/22343719
http://dx.doi.org/10.1038/nsmb.2251