Opposite Effects of Gene Deficiency and Pharmacological Inhibition of Soluble Epoxide Hydrolase on Cardiac Fibrosis

Arachidonic acid-derived epoxyeicosatrienoic acids (EETs) are important regulators of cardiac remodeling; manipulation of their levels is a potentially useful pharmacological strategy. EETs are hydrolyzed by soluble epoxide hydrolase (sEH) to form the corresponding diols, thus altering and reducing...

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Detalles Bibliográficos
Autores principales: Li, Lijuan, Li, Nan, Pang, Wei, Zhang, Xu, Hammock, Bruce D., Ai, Ding, Zhu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981766/
https://www.ncbi.nlm.nih.gov/pubmed/24718617
http://dx.doi.org/10.1371/journal.pone.0094092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981766/
https://www.ncbi.nlm.nih.gov/pubmed/24718617
http://dx.doi.org/10.1371/journal.pone.0094092

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