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Epigenetic Upregulation of Corticotrophin-Releasing Hormone Mediates Postnatal Maternal Separation-Induced Memory Deficiency

Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Early-life stress induced long-lasting functional adaptation of neuroendocrine hypothalamic-pituitary-adrenal axis, including neuropeptide corticotrophin-re...

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Detalles Bibliográficos
Autores principales: Wang, Aiyun, Nie, Wenying, Li, Haixia, Hou, Yuhua, Yu, Zhen, Fan, Qing, Sun, Ruopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981802/
https://www.ncbi.nlm.nih.gov/pubmed/24718660
http://dx.doi.org/10.1371/journal.pone.0094394