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Epigenetic Upregulation of Corticotrophin-Releasing Hormone Mediates Postnatal Maternal Separation-Induced Memory Deficiency
Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Early-life stress induced long-lasting functional adaptation of neuroendocrine hypothalamic-pituitary-adrenal axis, including neuropeptide corticotrophin-re...
Autores principales: | Wang, Aiyun, Nie, Wenying, Li, Haixia, Hou, Yuhua, Yu, Zhen, Fan, Qing, Sun, Ruopeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981802/ https://www.ncbi.nlm.nih.gov/pubmed/24718660 http://dx.doi.org/10.1371/journal.pone.0094394 |
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