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Targeting Insulin-Like Growth Factor 1 Leads to Amelioration of Inflammatory Demyelinating Disease

In patients with multiple sclerosis (MS) and in mice with experimental autoimmune encephalomyelitis (EAE), proliferating autoreactive T cells play an important role in the pathogenesis of the disease. Due to the importance of these myelin-specific T cells, these cells have been therapeutic targets i...

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Detalles Bibliográficos
Autores principales: Cusick, Matthew F., Libbey, Jane E., Trede, Nikolaus S., Fujinami, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981810/
https://www.ncbi.nlm.nih.gov/pubmed/24718491
http://dx.doi.org/10.1371/journal.pone.0094486