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Identification of a Role for the PI3K/AKT/mTOR Signaling Pathway in Innate Immune Cells

The innate immune system is the first line of host defense against infection and involves several different cell types. Here we investigated the role of the phosphatidylinositol 3 kinase (PI3K) signaling pathway in innate immune cells. By blocking this pathway with pharmacological inhibitors, we fou...

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Detalles Bibliográficos
Autores principales: Xie, Songbo, Chen, Miao, Yan, Bing, He, Xianfei, Chen, Xiwen, Li, Dengwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981814/
https://www.ncbi.nlm.nih.gov/pubmed/24718556
http://dx.doi.org/10.1371/journal.pone.0094496