Immune Dysregulation as a Cause of Autoinflammation in Fragile X Premutation Carriers: Link between FMRI CGG Repeat Number and Decreased Cytokine Responses

BACKGROUND: Increased rates of autoinflammatory and autoimmune disorders have been observed in female premutation carriers of CGG repeat expansion alleles of between 55–200 repeats in the fragile X mental retardation 1 (FMR1) gene. To determine whether an abnormal immune profile was present at a cel...

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Detalles Bibliográficos
Autores principales: Careaga, Milo, Rose, Destanie, Tassone, Flora, Berman, Robert F., Hagerman, Randi, Ashwood, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981824/
https://www.ncbi.nlm.nih.gov/pubmed/24718368
http://dx.doi.org/10.1371/journal.pone.0094475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981824/
https://www.ncbi.nlm.nih.gov/pubmed/24718368
http://dx.doi.org/10.1371/journal.pone.0094475

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