Cargando…

Generation and Characterization of Induced Pluripotent Stem Cells from Aid-Deficient Mice

It has been shown that DNA demethylation plays a pivotal role in the generation of induced pluripotent stem (iPS) cells. However, the underlying mechanism of this action is still unclear. Previous reports indicated that activation-induced cytidine deaminase (Aid, also known as Aicda) is involved in...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimamoto, Ren, Amano, Naoki, Ichisaka, Tomoko, Watanabe, Akira, Yamanaka, Shinya, Okita, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981863/
https://www.ncbi.nlm.nih.gov/pubmed/24718089
http://dx.doi.org/10.1371/journal.pone.0094735