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Generation and Characterization of Induced Pluripotent Stem Cells from Aid-Deficient Mice
It has been shown that DNA demethylation plays a pivotal role in the generation of induced pluripotent stem (iPS) cells. However, the underlying mechanism of this action is still unclear. Previous reports indicated that activation-induced cytidine deaminase (Aid, also known as Aicda) is involved in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981863/ https://www.ncbi.nlm.nih.gov/pubmed/24718089 http://dx.doi.org/10.1371/journal.pone.0094735 |