Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

Tissue mechanics regulate development and homeostasis and are consistently modified in tumor progression. Nevertheless, the fundamental molecular mechanisms through which altered mechanics regulate tissue behavior and the clinical relevance of these changes remain unclear. We demonstrate that increa...

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Detalles Bibliográficos
Autores principales: Mouw, Janna K, Yui, Yoshihiro, Damiano, Laura, Bainer, Russell O, Lakins, Johnathan N, Acerbi, Irene, Ou, Guanqing, Wijekoon, Amanda C, Levental, Kandice R, Gilbert, Penney M, Chen, Yunn-Yi, Weaver, Valerie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981899/
https://www.ncbi.nlm.nih.gov/pubmed/24633304
http://dx.doi.org/10.1038/nm.3497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981899/
https://www.ncbi.nlm.nih.gov/pubmed/24633304
http://dx.doi.org/10.1038/nm.3497

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