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Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression
Tissue mechanics regulate development and homeostasis and are consistently modified in tumor progression. Nevertheless, the fundamental molecular mechanisms through which altered mechanics regulate tissue behavior and the clinical relevance of these changes remain unclear. We demonstrate that increa...
Autores principales: | Mouw, Janna K, Yui, Yoshihiro, Damiano, Laura, Bainer, Russell O, Lakins, Johnathan N, Acerbi, Irene, Ou, Guanqing, Wijekoon, Amanda C, Levental, Kandice R, Gilbert, Penney M, Chen, Yunn-Yi, Weaver, Valerie M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981899/ https://www.ncbi.nlm.nih.gov/pubmed/24633304 http://dx.doi.org/10.1038/nm.3497 |
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