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Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease

Cell death and synapse dysfunction are two likely causes of cognitive decline in AD. As cells die and synapses lose their drive, remaining cells suffer an initial decrease in activity. Neuronal homeostatic synaptic scaling then provides a feedback mechanism to restore activity. This homeostatic mech...

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Detalles Bibliográficos
Autores principales: Rowan, Mark S., Neymotin, Samuel A., Lytton, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982056/
https://www.ncbi.nlm.nih.gov/pubmed/24765074
http://dx.doi.org/10.3389/fncom.2014.00039